Antipsychotic-induced extrapyramidal symptoms in patients with schizophrenia: associations with dopamine and serotonin receptor and transporter polymorphisms

Cüneyt Güzey; Maria Gabriella Scordo; Edoardo Spina; Veslem?y Malm Landsem; Olav Spigset

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Antipsychotic-induced extrapyramidal symptoms in patients with schizophrenia: associations with dopamine and serotonin receptor and transporter polymorphisms

机译：抗精神病药诱导的精神分裂症患者的锥体外系症状：与多巴胺和5-羟色胺受体及转运蛋白多态性的关联

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摘要

Little is known about the influence of polymorphisms of the dopamine and serotonin system on the risk for extrapyramidal symptoms (EPS) during treatment with antipsychotic drugs.

机译：关于多巴胺和5-羟色胺系统多态性对抗精神病药治疗期间锥体束外症状（EPS）风险的影响知之甚少。

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来源
《European Journal of Clinical Pharmacology》 |2007年第3期|233-241|共9页
作者
Cüneyt Güzey; Maria Gabriella Scordo; Edoardo Spina; Veslem?y Malm Landsem; Olav Spigset;
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作者单位

Department of Clinical Pharmacology St. Olav University Hospital Trondheim Norway;

Department of Medical Sciences Clinical Pharmacology Uppsala University Uppsala Sweden;

Department of Clinical and Experimental Medicine and Pharmacology University of Messina Italy and IRCCS Centro Neurolesi “Bonino-Pulejo” Messina Italy;

Department of Laboratory Medicine Children’s and Women’s Health Norwegian University of Science and Technology Trondheim Norway;

Department of Clinical Pharmacology St. Olav University Hospital Trondheim Norway;

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原文格式 PDF
正文语种 eng
中图分类
关键词
Dopamine receptors; Dopamine transporter; Serotonin receptors; Serotonin transporter; Polymorphism;

机译：多巴胺受体;多巴胺转运蛋白;5-羟色胺受体;5-羟色胺转运蛋白;多态性;

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专利

1. Antipsychotic-induced extrapyramidal symptoms in patients with schizophrenia: associations with dopamine and serotonin receptor and transporter polymorphisms. [J] . Guzey C, Scordo MG, Spina E, European journal of clinical pharmacology . 2007,第3期

机译：抗精神病药诱发的精神分裂症患者锥体外系症状：与多巴胺和5-羟色胺受体及转运蛋白多态性相关。
2. Risk factors for extrapyramidal symptoms during treatment with selective serotonin reuptake inhibitors, including cytochrome P-450 enzyme, and serotonin and dopamine transporter and receptor polymorphisms. [J] . Hedenmalm K, Guzey C, Dahl ML, Journal of clinical psychopharmacology . 2006,第2期

机译：选择性5-羟色胺再摄取抑制剂治疗期间出现锥体束外症状的危险因素，包括细胞色素P-450酶，5-羟色胺和多巴胺转运蛋白和受体多态性。
3. Lack of association between antipsychotic-induced extrapyramidal symptoms and polymorphisms in dopamine metabolism and transport genes. [J] . Gasso P, Mas S, Crescenti A, Psychiatry research . 2010,第1a2期

机译：抗精神病药诱发的锥体外系症状与多巴胺代谢和转运基因的多态性之间缺乏关联。
4. SEROTONIN RECEPTOR AND SEROTONIN REUPTAKE TRANSPORTER EXPRESSION IN PRIMARY AND METASTATIC CANINE OSTEOSARCOMA CELL LINES. [C] . Shay Bracha, Kenine E Comstock, Evan T Keller, Annual conference of the Veterinary Cancer Society . 2008

机译：血清素受体和血清素再摄取转运蛋白表达在原发性和转移性犬骨瘤细胞系中。
5. Sibling-based association study of dopamine transporter, serotonin transporter, and dopamine-4 receptor polymorphisms and disordered eating behavior in young adults. [D] . Sobik, Laura Elizabeth. 2007

机译：基于兄弟姐妹的多巴胺转运蛋白，血清素转运蛋白和多巴胺-4受体多态性与年轻人饮食行为紊乱的关联研究。
6. Association of CYP2D6 polymorphisms and extrapyramidal symptoms in schizophrenia patients receiving risperidone: a retrospective study [O] . Takahiro Ito, Kazuhiro Yamamoto, Fuminori Ohsawa, 2018

机译：CYP2D6基因多态性与接受利培酮治疗的精神分裂症患者锥体束外症状的关系：一项回顾性研究
7. Association of polymorphism in the dopamine receptors and transporter genes with hyperprolactinemia in patients with schizophrenia [O] . D. Osmanova, A.S. Boiko, O.Y. Fedorenko, 2017

机译：精神分裂症患者多巴胺受体与转运蛋白血症的多氨基受体和转运基因的关联

Antipsychotic-induced extrapyramidal symptoms in patients with schizophrenia: associations with dopamine and serotonin receptor and transporter polymorphisms

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