Study of the pharmacokinetics and intragastric pH of rabeprazole given as successive intravenous infusion to healthy Chinese volunteers

Yongqing Wang; Yaozong Yuan; Ling Meng; Hongwei Fan; Jianming Xu; Hongwen Zhang; Meifeng Wang; Hongyu Yuan; Ning Ou; Haibo Zhang

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Study of the pharmacokinetics and intragastric pH of rabeprazole given as successive intravenous infusion to healthy Chinese volunteers

机译：雷贝拉唑连续静脉输注中国健康志愿者的药代动力学和胃内pH的研究

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摘要

Objectives To investigate the pharmacokinetics and pharmacodynamics of rabeprazole (RPZ) given as successive intravenous infusion to healthy Chinese volunteers.

机译：目的研究雷贝拉唑（RPZ）连续静脉输注给健康的中国志愿者的药代动力学和药效学。

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来源
《European Journal of Clinical Pharmacology》 |2011年第1期|p.25-31|共7页
作者
Yongqing Wang; Yaozong Yuan; Ling Meng; Hongwei Fan; Jianming Xu; Hongwen Zhang; Meifeng Wang; Hongyu Yuan; Ning Ou; Haibo Zhang;
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正文语种 eng
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关键词
Rabeprazole – Pharmacokinetics – Proton pump inhibitors (PPIs) – Intragastric pH – Cytochrome P450 2C19 genotype;

机译：雷贝拉唑–药代动力学–质子泵抑制剂（PPI）–胃内pH –细胞色素P450 2C19基因型;

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专利

1. Study of the pharmacokinetics and intragastric pH of rabeprazole given as successive intravenous infusion to healthy Chinese volunteers. [J] . Wang Y, Yuan Y, Meng L, European journal of clinical pharmacology . 2011,第1期

机译：雷贝拉唑连续静脉输注给健康中国志愿者的药代动力学和胃内pH研究。
2. Influence of CYP2C19 on the relationship between pharmacokinetics and intragastric pH of omeprazole administered by successive intravenous infusions in Chinese healthy volunteers. [J] . Wang Y, Zhang H, Meng L, European journal of clinical pharmacology . 2010,第6期

机译：CYP2C19对中国健康志愿者连续静脉输注奥美拉唑药代动力学与胃内pH关系的影响。
3. Influence of CYP2C19 on the relationship between pharmacokinetics and intragastric pH of omeprazole administered by successive intravenous infusions in Chinese healthy volunteers [J] . Yongqing Wang, Hongwen Zhang, Ling Meng, European Journal of Clinical Pharmacology . 2010,第6期

机译：CYP2C19对中国健康志愿者连续静脉输注奥美拉唑药代动力学与胃内pH关系的影响
4. Serum and nail pharmacokinetic studies of itraconazole after mutiple oral dosing to 9 healthy chinese volunteers [C] . Chen Xiulan, Bai Lin, Lu xiaochuna, Proceedings of the Fourth China-Jpan international congress of mycology . 1998

机译：对9名健康中国志愿者进行多次口服给药后伊曲康唑的血清和指甲药代动力学研究
5. Propafenone pharmacokinetics: GLC-ECD analysis; metabolic induction by phenobarbital in nonsmoking and smoking healthy volunteers; protein binding; pharmacodynamics in patients [D] . Chan, Grace Lap-Yu 1989

机译：普罗帕酮药代动力学：GLC-ECD分析；非吸烟和吸烟健康志愿者的苯巴比妥诱导代谢；蛋白质结合；患者的药效学
6. Pharmacokinetics of Cefozopran by Single and Multiple Intravenous Infusions in Healthy Chinese Volunteers [O] . G. L. Wu, J. Z. Shentu, H. L. Zhou, 2015

机译：一次和多次静脉输注头孢唑烷对健康中国志愿者的药代动力学
7. The pharmacokinetics and bioavailability of rabeprazole following single intravenous infusion and oral administration in healthy Chinese volunteers [O] . Ruihua Shi, Xiyong Zhang, Dewang Wang, 2010

机译：雷贝拉唑单次静脉输注和口服后对健康中国志愿者的药代动力学和生物利用度

Study of the pharmacokinetics and intragastric pH of rabeprazole given as successive intravenous infusion to healthy Chinese volunteers

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