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首页> 外文期刊>European Heart Journal >Influence of functional deficiency of complement mannose-binding lectin on outcome of patients with acute ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention
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Influence of functional deficiency of complement mannose-binding lectin on outcome of patients with acute ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention

机译:补体甘露糖结合凝集素功能缺失对急性ST段抬高型心肌梗死初次经皮冠状动脉介入治疗患者预后的影响

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Aims Experimental data point towards a favourable effect of low serum concentrations of complement mannose-binding lectin (MBL) on myocardial ischaemia/reperfusion (I/R) injury. As comparable data on the role of MBL in human I/R injury is lacking, we investigated the influence of low serum MBL concentrations on mortality of patients with acute ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI).
机译:目的实验数据表明低血清补体甘露糖结合凝集素(MBL)的血清浓度对心肌缺血/再灌注(I / R)损伤具有良好的作用。由于缺乏有关MBL在人I / R损伤中作用的可比数据,我们调查了低血清MBL浓度对接受初次经皮冠状动脉介入治疗(PCI)的急性ST抬高型心肌梗死(STEMI)患者死亡率的影响。

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  • 来源
    《European Heart Journal》 |2010年第10期|p.1181-1187|共7页
  • 作者单位

    Internal Medicine and Clinical Immunology Laboratory, University Hospital Basel, Petersgraben 4, CH—4031, Basel, Switzerland;

    Montreal Heart Institute, Montreal, Quebec, Canada;

    Duke Clinical Research Institute, Durham, NC, USA;

    Duke University Medical Centre, Durham, NC, USA;

    Department of Medicine, University of Alberta, Edmonton, Alberta, Canada;

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