Effects of Ethynylestradiol on the Reproductive Physiology in Zebrafish(Danio rerio): Time Dependency and Reversibility

摘要

Environmental pollution with natural or synthetic estrogens may pose a serious threat to reproduction of wildlife species. This study describes the effects of 17-α-ethynylestradiol(EE2) on fish reproductive organs in a laboratory model. Adult zebrafish Were semistatically exposed to nominal concentrations of 0, 10, and 25 ng/L EE2 for 24 d and then transferred to EE2-free medium. Gonadosomatic index(GSI), plasma vitellogenin concentration(VTG), and histology of the gonads (control and 10 ng/L only) Were examined as function of time. It was found that EE2 has an adverse impact on both male and female reproductive organs.