Levels of Hexabromocyclododecane in Harbor Porpoises and Common Dolphins from Western European Seas,with Evidence for Stereoisomer-Specific Biotransformation by Cytochrome P450

摘要

Commercial hexabromocyclododecane(HBCD)is a high-production-volume flame-retardant applied in polystyrene foams.It contains three stereoisomers,of which gamma-HBCD always dominates.Here we report on the levels of HBCD in blubber of harbor porpoise and common dolphin from different European seas.The highest total(SIGMA)-HBCD levels were measured in harbor porpoises stranded on the Irish and Scottish coasts of the Irish Sea(median concentration 2.9mug(g of lipid)~(-1))and the northwest coast of Scotland(median concentration 5.1 mug(g of lipid)~(-1)).The median levels in other areas were,for the harbor porpoise south coast of Ireland,1.2 mug(g of lipid)~(-1),for the coasts of The Netherlands,Belgium,and France north of Calais(southern North Sea),1.1 mug(g of lipid)~(-1),for the east coast of Scotland(northern North Sea),0.77 mug(g of lipid)~(-1),and,for Galicia(Spain),0.1 mug(g of lipid}~(-1).The median levels for the common dolphin were,for west coast of Ireland,0.9 mug(g of lipid)~(-1),for the French coast of the English Channel between Normandy and Brest,0.4 mug(g of lipid)~(-1),and,for Galicia,0.2 mug(g of lipid)~(-1).