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Discoveringthe Texas molecule

机译:发现德克萨斯分子

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What inspired you to become a chemist?rnMy love for chemistry started in the seventh grade at school when I had the chance to do some experiments as part of the curriculum. Also, my father was a physicist and we had a small laboratory in our house. I was able do experiments in there, such as making esters. These exploits finally came to an end when I successfully synthesised nitroglycerine and blew up half the lab!rnWhat is the most significant aspect of your work?rnOver the course of my career, it has been the use of new macrocycles for drug development. However, right now, it is the transition between supramolecular chemistry and polymer chemistry. We are particularly excited about a joint project with Chris Bielawski's group at The University of Texas. It combines the chemistry of various specific neutral anion receptors (these are more biocompatible than charged receptors) with polymeric materials. This is allowing us to couple the specificity of the receptors with the well controlled hydrophobic environment of polymers. We can extract ions into organic media using receptors that would never work by themselves.
机译:是什么促使你成为一名化学家?我对化学的热爱始于学校七年级,当时我有机会作为课程的一部分进行一些实验。另外,我父亲是一名物理学家,我们家里有一个小实验室。我能够在那里进行实验,例如制造酯。当我成功地合成了硝酸甘油并炸毁了一半的实验室时,这些漏洞终于告一段落了。您工作中最重要的方面是什么?整个职业生涯中,一直在使用新的大环化合物进行药物开发。然而,目前,这是超分子化学和高分子化学之间的过渡。我们特别高兴与德克萨斯大学Chris Bielawski小组的合作项目。它结合了各种特定的中性阴离子受体(与带电受体相比具有更高的生物相容性)与聚合物材料的化学性质。这使我们能够将受体的特异性与聚合物的疏水性良好控制的环境相结合。我们可以使用永远无法自行工作的受体将离子提取到有机介质中。

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