首页> 外国专利> 1435 molecule, 559 molecule, 34021 molecule, 44099 molecule, 25278 molecule, 641 molecule, 260 molecule, 55089 molecule, 21407 molecule, 42032 molecule, 46656 molecule, 62553 molecule, 302 molecule, 323 molecule, 12303 molecule, 985 molecule, 13237 molecule And compositions for the treatment of urological diseases using, 13601, 18926, 318, 2058 or 6351 molecules

1435 molecule, 559 molecule, 34021 molecule, 44099 molecule, 25278 molecule, 641 molecule, 260 molecule, 55089 molecule, 21407 molecule, 42032 molecule, 46656 molecule, 62553 molecule, 302 molecule, 323 molecule, 12303 molecule, 985 molecule, 13237 molecule And compositions for the treatment of urological diseases using, 13601, 18926, 318, 2058 or 6351 molecules

机译:1435分子,559分子,34021分子,44099分子,25278分子,641分子,260分子,55089分子,21407分子,42032分子,46656分子,62553分子,302分子,323分子,12303分子,985分子,13237分子以及使用13601、18926、318、2058或6351分子治疗泌尿系统疾病的组合物

摘要

The present invention relates to methods for the diagnosis and treatment of a urological disorder or urological disorders. Specifically, the present invention identifies the differential expression of 1435, 559, 34021, 44099, 25278, 641, 260, 55089, 21407, 42032, 46656, 62553, 302, 323, 12303, 985, 13237, 13601, 18926, 318, 2058 and 6351 genes in tissues relating to urological disorders, relative to their expression in normal, or non-urological disorders, and/or in response to manipulations relevant to a urological disorder. The present invention describes methods for the diagnostic evaluation and prognosis of various urological disorders, and for the identification of subjects exhibiting a predisposition to such conditions. The invention also provides methods for identifying a compound capable of modulating a urological disorder or urological disorders. The present invention also provides methods for the identification and therapeutic use of compounds as treatments of urological disorders.
机译:本发明涉及用于诊断和治疗一种或多种泌尿系统疾病的方法。具体而言,本发明识别了1435、559、34021、44099、25278、641、260、55089、21407、42032、46656、62553、302、323、12303、985、13237、13601、18926、318,与泌尿系统疾病有关的组织中的2058和6351基因,相对于它们在正常或非泌尿系统疾病中的表达,和/或响应于与泌尿系统疾病相关的操作。本发明描述了用于各种泌尿系统疾病的诊断评估和预后,以及用于鉴定表现出对这种状况易感性的受试者的方法。本发明还提供了鉴定能够调节一种或多种泌尿科疾病的化合物的方法。本发明还提供了鉴定和治疗用作泌尿科疾病的化合物的方法。

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