Final Height and Growth Hormone Secretion after Bone Marrow Transplantation in Children

摘要

Growth hormone (GH) deficiency has been regarded as a principal determinant for growth failure fol- lowing bone marrow transplantation (BMT). We herein analyzed final height and GH secretion in the patients who received BMT during childhood. The study on final height in 30 patients (23 males; 19 with malignant disease) who underwent BMT before or at the onset of puberty showed the following findings: (1) Final height SD score (SDS) significantly decreased compared to pretreatment height SDS.