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首页> 外文期刊>Ecotoxicology and Environmental Safety >Corrigendum to 'Correlation of pesticide exposure from dietary intake and bio-monitoring: The different sex and socio-economic study of children'
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Corrigendum to 'Correlation of pesticide exposure from dietary intake and bio-monitoring: The different sex and socio-economic study of children'

机译:“膳食摄入和生物监测中农药暴露的相关性:儿童的不同性别和社会经济研究”的勘误

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Exposure to organophosphorus pesticides was assessed though bio-monitoring of urinary dialkyl phosphate metabolites to characterize children's exposure to pesticides. No reports have been found which evaluate exposure of pesticides among adolescents of different sexes. The primary objective was to develop a coupled exposure–dose modeling approach that can be used to determine the metabolite concentrations. Related objective was to determine any significant changes of pesticide exposure among the adolescents of different sexes. The primary objective was to develop a coupled exposure-dose modeling approach to determine the metabolites concentrations to keep children's urine metabolites levels below specified values considering exposures from water, and the food related objective was to determine any significant changes of pesticide exposure among the adolescents of different sexes. We recruited a sample of 377 children (188 boys, 189 girls) ages 6–10 and 11–15 years from Hyderabad, India for urine collection. Results showed that the mean concentrations of dialkyl phosphate metabolites in first morning first urine samples (3.05 µmol L−1) were strongly correlated with concentrations of the same-day 24-h samples (1.7 µmol L−1) ( r = 0.997, modelR2≈ 0.994,p < 0.00) with 99.4% accuracy. Irrespective of similar amounts of conventional food consumption, girls showed 87.5% of detection frequency of DAP metabolites which was higher than the 74% detection frequency of DAP metabolites among boys. The female group showed (87%) higher pesticide metabolite levels than boys. This report may help to focus on new studies of the connection between adolescents of different sex and organophosphorus metabolite exposure and to develop an exposure database to facilitate health risk assessment in our day-to-day environment.
机译:通过生物监测尿中的磷酸二烷基酯代谢物来评估儿童对有机磷农药的暴露情况,以表征儿童对农药的暴露情况。没有发现评估不同性别青少年接触农药的报告。主要目标是开发一种可用于确定代谢物浓度的暴露-剂量耦合建模方法。相关目标是确定不同性别青少年之间农药暴露的任何重大变化。主要目标是开发一种剂量-剂量耦合的模拟方法,确定代谢物的浓度,以考虑到水的接触,使儿童尿液中的代谢物水平保持在规定值以下;与食物有关的目标是,确定儿童中青少年农药暴露的任何重大变化。不同性别。我们从印度海得拉巴抽取了377名6-10岁和11-15岁的儿童(188名男孩,189名女孩)进行尿液收集。结果表明,第一个早晨的第一尿液样本中磷酸二烷基酯代谢物的平均浓度(3.05μmol·L-1)与当日的24小时样本浓度(1.7μmol·L-1)(r = 0.997,模型R2)密切相关。 ≈0.994,p <0.00),准确度为99.4%。不论常规食品的消费量如何,女孩的DAP代谢物检出频率为87.5%,高于男孩中DAP代谢物检出频率的74%。女性组的农药代谢物水平比男孩高(87%)。该报告可能有助于重点研究有关不同性别的青少年与有机磷代谢物暴露之间关系的新研究,并建立暴露数据库以促进我们在日常环境中的健康风险评估。

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