Uptake, Toxicity, and Effects on Detoxication Enzymes of Atrazine and Trifluoroacetate in Embryos of Zebrafish

摘要

The uptake, toxicity, and elimination of atrazine and trifluoroacetate (TFA) were studied in early life stages of the zebrafish (Danio rerio). Furthermore, the effects of these xenobiotics on solube (S) and microsomal (m) glutathione Stransfereases (GST) of zebrafish embryos were investigated using 1-chloro-2, 4-dinitrobenzene (CDNB), 1,2-dichloro-4-nitrobenzene(DCNB), and [~(14)C]Atrazine was taken up by the embryos within seconds, unhindered by the chorions. It accumulated in the embryos by a factor of 19 after 24 h of exposure time. LC_(50) (48h) was determined at 36.8 mg/L.