The Generation of the Human mAb RabD4 Specific to the Rabies Virus Glycoprotein and Characterization Thereof

Ilina E. N.; Solopova E. V.; Aliev T. K.; Larina M. V.; Balabashin D. S.; Varlamov N. E.; Dolgikh D. A.; Sveshnikov P. G.; Kirpichnikov M. P.

首页> 外文期刊>Doklady biochemistry & biophysics >The Generation of the Human mAb RabD4 Specific to the Rabies Virus Glycoprotein and Characterization Thereof

【24h】

The Generation of the Human mAb RabD4 Specific to the Rabies Virus Glycoprotein and Characterization Thereof

机译：狂犬病毒糖蛋白特异的人单克隆抗体RabD4的产生及其表征

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

We generated a novel human neutralizing human mAb RabD4 against rabies virus glycoprotein using in vitro stimulation of human peripheral B cells produced by immunized donor. The human mAb RabD4 showed a high antigen-binding activity and virus-neutralizing activity in the FAVN test with the CVS-11 rabies virus.

机译：我们通过体外刺激免疫供体产生的人外周血B细胞，产生了针对狂犬病毒糖蛋白的新型人中和人mAb RabD4。在用CVS-11狂犬病病毒进行的FAVN测试中，人mAb RabD4具有很高的抗原结合活性和病毒中和活性。

著录项

来源
《Doklady biochemistry & biophysics》 |2019年第maraaapra期|126-128|共3页
作者
Ilina E. N.; Solopova E. V.; Aliev T. K.; Larina M. V.; Balabashin D. S.; Varlamov N. E.; Dolgikh D. A.; Sveshnikov P. G.; Kirpichnikov M. P.;
展开▼
作者单位

Moscow MV Lomonosov State Univ, Moscow 119991, Russia;

All Russia Res Ctr Mol Diagnost & Therapy, Moscow 117149, Russia;

Moscow MV Lomonosov State Univ, Moscow 119991, Russia;

Russian Acad Sci, Shemyakin Ovchinnikov Inst Bioorgan Chem, Moscow 117997, Russia;

Russian Acad Sci, Shemyakin Ovchinnikov Inst Bioorgan Chem, Moscow 117997, Russia;

All Russia Res Ctr Mol Diagnost & Therapy, Moscow 117149, Russia;

Moscow MV Lomonosov State Univ, Moscow 119991, Russia|Russian Acad Sci, Shemyakin Ovchinnikov Inst Bioorgan Chem, Moscow 117997, Russia;

All Russia Res Ctr Mol Diagnost & Therapy, Moscow 117149, Russia;

Moscow MV Lomonosov State Univ, Moscow 119991, Russia|Russian Acad Sci, Shemyakin Ovchinnikov Inst Bioorgan Chem, Moscow 117997, Russia;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类
关键词

相似文献

外文文献
中文文献
专利

1. Generation and characterization of neutralizing human recombinant antibodies against antigenic site II of rabies virus glycoprotein [J] . Sun L., Chen Z., Yu L., Applied Microbiology and Biotechnology . 2013,第2期

机译：抗狂犬病毒糖蛋白抗原位点II的中和人重组抗体的产生和表征
2. Generation and characterization of neutralizing human recombinant antibodies against antigenic site II of rabies virus glycoprotein [J] . Lina Sun, Zhe Chen, Li Yu, Applied Microbiology and Biotechnology . 2012,第2期

机译：抗狂犬病病毒糖蛋白Ⅱ号抗原位点的中和人重组抗体的产生和鉴定
3. Generation and characterization of human monoclonal antibodies to G5, a linear neutralization epitope on glycoprotein of rabies virus, by phage display technology. [J] . Zhao XL, Yin J, Chen WQ, Microbiology and Immunology . 2008,第2期

机译：通过噬菌体展示技术生成和表征针对G5的人单克隆抗体，G5是狂犬病毒糖蛋白上的线性中和表位。
4. NanoESI Gas-phase Electrophoretic Mobility Analysis (GEMMA) of an Intact Specific Human Rhinovirus (HRV)-Monoclonal Antibody (mAB) Complex [C] . Christian Laschober, Dieter Blaas, Wladyslaw W. Szymanski, ASMS Conference on Mass Spectrometry and Allied Topics . 2006

机译：完整的特异性人鼻病毒（HRV）-monoclon抗体（MAB）复合物的纳米气相电泳迁移率分析（Gemma）
5. Characterization of epitopes on the rabies virus glycoprotein by selection and analysis of escape mutants. [D] . Fallahi, Firouzeh. 2005

机译：通过选择和分析逃逸突变体来表征狂犬病毒糖蛋白上的抗原决定簇。
6. Rabies virulence: effect on pathogenicity and sequence characterization of rabies virus mutations affecting antigenic site III of the glycoprotein. [O] . I Seif, P Coulon, P E Rollin, 1985

机译：狂犬病毒力：影响狂犬病毒变异的致病性和序列表征影响糖蛋白的抗原位点III。
7. The generation of the human mab RabD4 specific to the rabies virus glycoprotein and characterization thereof [O] . Е. N. Ilina, E. V. Solopova, Т. К. Aliev, 2019

机译：对狂犬病病毒糖蛋白特异的人mAb rabd4的产生和其特征

The Generation of the Human mAb RabD4 Specific to the Rabies Virus Glycoprotein and Characterization Thereof

摘要

著录项

相似文献

相关主题

期刊订阅