Adaptation of Mycoplasmas to Environmental Conditions: Features of the Proteome Shift in Acholeplasma laidlawii PG8 at Persistent Exposure to Stressors

摘要

Acholeplasma laidlawii (Class Mollicutes) is a ubiquitous mycoplasma. The bacteria, which is found in soil, sewage, and tissues of higher eukaryotes, is a major contaminant of cell cultures and the causative agent of phytomycoplasmoses [1]. The control of mycoplasmal infections is a serious problem whose solution is associated with the elucidation of the molecular-genetic bases of adaptation of mycoplasmas to environmental conditions, which determines the broad distribution of these bacteria in nature and manifestations of pathogenicity [2-4].