Exported Mycoplasmal Proteins: Proteome of Extracellular Membrane Vesicles of Acholeplasma laidlawii PG8

摘要

Ample theoretical and experimental data for myco-plasmas obtained in recent years determined substantial progress in understanding the molecular and cellular biology of the smallest prokaryotes. Genome-transcriptome-proteome profiling and nanoscopic analysis made it possible to identify stress-reactive genes and proteins in a number of mycoplasmas. It was shown that adaptation to environmental conditions, cell-cell interactions, and pathogenicity of these microorganisms are largely associated with the extracellular membrane vesicles of these bacteria. Extracellular vesicles (EVs) are the key component of the bacterial secretome. First discovered several decades ago in the Gram-negative bacteria, they have recently been identified in the Gram-positive bacteria , archaea, and mycoplasmas and became the focus of attention of researchers.