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首页> 外文期刊>Diabetologia >Oligodeoxynucleotide IMT504 induces a marked recovery in a streptozotocin-induced model of diabetes in rats: correlation with an early increase in the expression of nestin and neurogenin 3 progenitor cell markers
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Oligodeoxynucleotide IMT504 induces a marked recovery in a streptozotocin-induced model of diabetes in rats: correlation with an early increase in the expression of nestin and neurogenin 3 progenitor cell markers

机译:寡脱氧核苷酸IMT504在链脲佐菌素诱导的大鼠糖尿病模型中诱导明显恢复:与巢蛋白和神经生成素3祖细胞表达的早期增加相关

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摘要

Aims/hypothesis IMT504 is an oligonucleotide that promotes tissue repair in bone injury and neuropathic pain models by stimulating progenitor cells. Here we evaluated the effect of IMT504 on the recovery of islet function in a streptozotocin (STZ)-induced model of diabetes in the rat.
机译:目的/假设IMT504是一种寡核苷酸,可通过刺激祖细胞来促进骨损伤和神经性疼痛模型中的组织修复。在这里,我们评估了IMT504对链脲佐菌素(STZ)诱导的大鼠糖尿病模型中胰岛功能恢复的影响。

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