Brief Genetics Report: No Association Between the Friedreich's Ataxia Gene and NIDDM in the French Population

摘要

Recent advances in molecular genetics have allowed the identification of genetic anomalies associated with some monogenic forms of NIDDM, such as maturity-onset diabetes of the Young (MODY) or maternally inherited diabetes associated With deafness (MIDD). However, these genes do not account For a great part of the genetic determinism of the common Forms of NIDDM. A candidate gene approach studying the Genes or chromosomal areas involved in syndromes associ- Ated with diabetes, such as ataxia telangiectasia (1) or Friedreich's ataxia (FRDA) (2), may contribute to the identi- Fication of suseptibility genes for NIDDM.