首页> 外文期刊>Diabetes >The microRNA Signature in Response to Insulin Reveals Its Implication in the Transcriptional Action of Insulin in Human Skeletal Muscle and the Role of a Sterol Regulatory Element-Binding Protein-1c/Myocyte Enhancer Factor 2C Pathway
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The microRNA Signature in Response to Insulin Reveals Its Implication in the Transcriptional Action of Insulin in Human Skeletal Muscle and the Role of a Sterol Regulatory Element-Binding Protein-1c/Myocyte Enhancer Factor 2C Pathway

机译:响应胰岛素的microRNA特征揭示了其在人类骨骼肌中的转录作用中的意义以及甾醇调节元素结合蛋白1c /心肌细胞增强因子2C途径的作用

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摘要

Factors governing microRNA expressions in response to changes of cellular environment are still largely unknown. Our aim was to determine whether insulin, the major hormone controlling whole-body energy homeostasis, is involved in the regulation of microRNA expressions in human skeletal muscle.
机译:响应细胞环境变化而控制microRNA表达的因素仍是未知之数。我们的目标是确定胰岛素(控制全身能量稳态的主要激素)是否参与人类骨骼肌中microRNA表达的调节。

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  • 来源
    《Diabetes》 |2009年第11期|p.2555-2564|共10页
  • 作者单位

    Aurélie Granjon,1 Marie-Paule Gustin,2 Jennifer Rieusset,1 Etienne Lefai,1 Emmanuelle Meugnier,1 Isabelle Güller, ' Catherine Cerutti,2 Christian Paultre,2 Emmanuel Disse,3,4 Rémi Rabasa-Lhoret,5 Martine Laville,1,3,4 Hubert Vidal,1,3,4 and Sophie Rome1From the 1 Iinstitute, de la Recherche Agronomique (INKA) 1235, INSERM 870. INSA-Lyon, Régulations Metaboliques Nutrition et Diabète, Université Lyon. Oullins, France: 2 INSERM ERI22/EA 4173, Biostatistiques, l'niversité Lyon, Lyon, France, the 3 Hospices Civils de Lyon, Service de Diabetologie et Nutrition, Hôpital Edouard-Herriot, Lyon, France, the 4 Centre de Recherche en Nutrition Humaine Rhône-Alpes, Oullins, Frame: and the 5 Chaire de recherche J-A DeSève. Institut «le Recherches Cliniques de Montréal, Montréal, Québec, Canada.Corresponding author: Sophie Rome, srome@univ-lyonl.fr.Received 5 February 2009 and accepted 5 August 2000. Published ahead of print at http://diabetes.diabetesjournals.org on 31 August 2009. DOI: 10.23377db09-0165.© 2009 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommoris.org/licenses/by -nc-nd/3.0/ for details.The costs of publication of this article were defrayed in port by the payment of page charges. This article must therefore be hereby marked "advertisement" in accordance with 18 U.S.C. Section 17th solely in indicate this fact.,;

  • 收录信息 美国《科学引文索引》(SCI);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
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  • 入库时间 2022-08-17 13:45:55

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