首页> 外文期刊>Diabetes >Restoration of Hepatic Glucokinase Expression Corrects Hepatic Glucose Flux and Normalizes Plasma Glucose in Zucker Diabetic Fatty Rats
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Restoration of Hepatic Glucokinase Expression Corrects Hepatic Glucose Flux and Normalizes Plasma Glucose in Zucker Diabetic Fatty Rats

机译:肝葡萄糖激酶表达的恢复可纠正祖克糖尿病肥胖大鼠的肝葡萄糖通量并使血浆葡萄糖正常化。

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摘要

We examined in 20-week-old Zucker diabetic fatty (ZDF) rats whether restoration of hepatic glucokinase (GK) expression would alter hepatic glucose flux and improve hyperglycemia.
机译:我们在20周大的Zucker糖尿病脂肪(ZDF)大鼠中检查了恢复肝葡萄糖激酶(GK)表达是否会改变肝葡萄糖通量并改善高血糖症。

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  • 来源
    《Diabetes》 |2009年第1期|p.78-86|共9页
  • 作者单位

    Tracy P. Torres,1 ReEtta L. Catlin,1 Robert Chan,1 Yuka Fnjimoto,1 Noriyasu Sasaki,1 Richard L. Printz,1 Christopher B. Newgard,2 and Masakazu Shiota1From the 'Department of Molecular Physiology and Biophysics, Vanderbilt Universiry School of Medicine, Nashville, Tennessee, and 2Sarah W. Stedman Nutrition and Metabolism Center, Duke Universiry Medical Center, Durham, North Carolina.Corresponding author. Masakazu Shiota, masakazu.shiota@vanderbilt.edu.Received 19 August 2008 and accepted 11 October 2008.T.P.T., R.L.C, and R.C. contributed equaUy to this work.Published ahead of print at http://diabetes.diabetesjoumals.org on 24 October 2008. DOI: 10.2337/db08-1119.© 2009 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http:/creativecommons.org/licenses/by -nc-nd/3.0/ for details.The costs of publication of this article were defrayed in part by the payment of page charges. This article must therefore be hereby marked "advertisement" in accordance with 18 U.S.C. Section 1734 solely to indicate this fact.,;

  • 收录信息 美国《科学引文索引》(SCI);美国《化学文摘》(CA);
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  • 正文语种 eng
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  • 入库时间 2022-08-17 13:45:45

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