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Impact of Age on the Relationships of Brown Adipose Tissue With Sex and Adiposity in Humans

机译:年龄对人棕色脂肪组织与性别和肥胖关系的影响

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摘要

Brown adipose tissue (BAT) regulates energy homeostasis and fat mass in mammals and newborns and, most likely, in adult humans. Because BAT activity and BAT mass decline with age in humans, the impact of BAT on adiposity may decrease with aging. In the present study we addressed this hypothesis and further investigated the effect of age on the sex differences in BAT activity and BAT mass.
机译:棕色脂肪组织(BAT)调节哺乳动物和新生儿以及最有可能在成年人中的能量稳态和脂肪量。由于BAT活性和BAT质量随人类年龄的增长而下降,因此BAT对肥胖的影响可能随着年龄的增长而降低。在本研究中,我们解决了这一假设,并进一步研究了年龄对BAT活性和BAT质量的性别差异的影响。

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  • 来源
    《Diabetes》 |2010年第7期|p.1789-1793|共5页
  • 作者单位

    Christina Pfannenberg,1 Matthias K. Werner,1 Sabine Ripkens,1 Irina Stef,1 Annette Deckert,1 Maria Schmadl,1 Matthias Reimold,2 Hans-Ulrich Häring,3 Claus D. Claussen,1 and Norbert Stefan3From the 1 Department of Diagnostic and Interventional Radiology. University of Tübingen, Tübingen, Germany, 2 Nuclear Medicine. University of Tübingen, Tübingen, Germany, 'Department of Internal Medicine, Division of Endocrinology, Diabetology, Vascular Medicine, Nephrology and Clinical Chemistry, University of Tübingen, Tübingen, Germany.Corresponding author: Norbert Stefan, norbert.stefan@med.um-tuebingen.de.Received 2 January 2010 and accepted 15 March 2010. Published ahead of print at http://diabetes.diabetesjounials.org on 27 April 2010. DOI: 10.2337/db 10-0004.C. P. and M.K.W. contributed equally to the present work.© 2010 by the American Diabetes Association. Readers may use Ulis article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. Sec http://cTeativccnnmmns.orp .icenses/hy -nc-nd/3.0/ for details.The costs of publication of this article were defrayed in part by the payment of page charges. This article must therefore be hereby marked "advertisement" in accordance with 18 U.S.C. Section 1734 solely io indicate this fad.,;

  • 收录信息 美国《科学引文索引》(SCI);美国《化学文摘》(CA);
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  • 正文语种 eng
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  • 入库时间 2022-08-17 13:45:38

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