Corneal Confocal Microscopy as a Measure of Diabetic Neuropathy

摘要

Distal symmetric polyneuropathy is the most common pattern of nerve injury in patients with diabetes (1,2). In fact, up to 50% of patients with diabetes will develop distal symmetric polyneuropathy at some point during their illness (3). Currently, the only effective treatment to prevent this prevalent condition is glucose control (4). Unfortunately, demonstrating an improvement in neuropathy over time has been much more difficult to achieve than preventing progression (5). Possible explanations for the lack of improvement in outcome measures include a lack of an effective treatment and/ or a lack of a sensitive test for nerve fiber repair.