Hepatic necrosis following yttrium-90 radioembolization for hepatocellular carcinoma in a patient with a recent history of external radiotherapy

摘要

Hepatobiliary complications from yttrium-90 ( 90 Y) radioembolization have been described previously but are often clinically inconsequential. This report describes the case of a patient in whom a large area of hepatic necrosis occurred after the patient underwent both stereotactic body radiotherapy and glass-based 90 Y radioembolization for the management of hepatocellular carcinoma. This case suggests that 90 Y microspheres can cause severe local hepatic injury when administered after external radiotherapy.