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An Examination of National Cancer Risk Based on Monitored Hazardous Air Pollutants

机译:基于受监测的危险空气污染物的国家癌症风险检查

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Background: Hazardous air pollutants, or air toxics, are pollutants known to cause cancer or other serious health effects. Nationwide cancer risk from these pollutants is estimated by the U.S. EPA National Air Toxics Assessment. However, these model estimates are limited to the totality of the emissions inventory used as inputs, and further, they cannot be used to examine spatial and temporal trends in cancer risk from hazardous air pollutants. Objectives: To complement model estimates of nationwide cancer risk, we examined trends in cancer risk using monitoring data from 2013 to 2017 across the 27 U.S. National Air Toxics Trends Stations. Methods: For each monitoring site, we estimated cancer risk by multiplying the annual concentration for each monitored pollutant by its corresponding unit risk estimate. We examined the 5-y average (2013–2017) cancer risk across sites and the population levels and demographics within 1-mi of the monitors, as well as changes in estimated cancer risk over time. Finally, we examined changes in individual pollutant concentrations and their patterns of covariance. Results: We found that the total estimated cancer risk is higher for urban vs. rural sites, with the risk at seven urban sites (of 21) above 75 in 1 million. Furthermore, while most pollutant concentrations have not changed over the time period explored, we found 38 site-pollutant combinations that significantly declined and 12 that significantly increased between 2013 and 2017. We also identified a positive correlation between estimated cancer risk and percent of the population within 1-mi of a monitor that is low income. Discussion: Long-term trends show that annual mean concentrations of most measured air toxics have declined. Our evaluation of a more recent snapshot in time finds that most pollutant concentrations have not changed from 2013 to 2017. This analysis of cancer risk based on monitored values provides an important complement to modeled nationwide cancer risk estimates and can further inform future approaches to mitigate risk from exposure to hazardous air pollutants.
机译:背景:危险的空气污染物或空气毒品,是众所周知的污染物,导致癌症或其他严重的健康影响。美国EPA国家航空毒素评估估计这些污染物的全国癌症风险。然而,这些模型估计仅限于用作输入的排放库存的总体,进一步,它们不能用于检查癌症风险的空间和时间趋势来自危险空气污染物。目标:为了补充全国范围内癌症风险的模型估算,我们在2013年至2017年在美国国家空中毒素趋势站中检查了2013年至2017年的监测数据的趋势。方法:对于每个监测网站,我们通过将每种监测污染物的年浓度乘以其相应的单位风险估算来估计癌症风险。我们在监视器的1-Mi内审查了5-y平均(2013-2017)癌症风险以及人口水平和人口统计学,以及估计癌症风险随时间的变化。最后,我们检查了个性污染物浓度的变化及其协方差模式。结果:我们发现,城市与农村地点的估计总癌症风险较高,七个城市网站(21)以上的七个危险为100万元。此外,虽然大多数污染物浓度在探索的时间段内没有改变,但我们发现38个现场污染物组合,显着下降,12年间,2013年至2017年之间明显增加。我们还确定了估计癌症风险与人口百分比之间的正相关性在低收入的显示器的1英里范围内。讨论:长期趋势表明,大多数测量的空气毒素的年平均浓度已下降。我们对时间最近的快照的评估发现,大多数污染物浓度从2013年到2017年没有改变。这种基于受监测价值的癌症风险分析对全国范围的癌症风险估计的建模提供了重要的补充,并可以进一步了解减轻风险的未来方法从暴露于危险空气污染物。

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