A Review on Benzoxazole Containing Heterocyclic Compounds as a Wonder Medication for Thousands of Ailments”

摘要

The benzoxazole is a heterocyclic aromatic organic compound. It is a vital pharmacophore and honoured structure in medicinal chemistry. It plays a very imperative role with quite useful therapeutic activities such as antiulcers, antihypertensives, analgesic, antiinflammatory, anti-virals, antifungals, anticancer, antidepressant activity, antilishmanial activity, anticonvulsant activity, antitubercular activity, antitumor activity, The review of the literature reveals that the benzoxazole derivatives are marvellously effective compounds and a large number of reviews available for biochemical and pharmacological studies established that their molecules are useful against a wide variety of microorganisms. Because of their prominence, the techniques for their synthesis have become an attention of synthetic organic chemists. Therefore, in the contemporary review we tried to assemble the chemistry of different derivative of substituted benzoxazole as well as various pharmacological activities and some of the important methodologies used for the synthesis.