REVERSAL OF EPIDURAL XYLAZINE IN EGYPTIAN WATER BUFFALO (BUBALUS BUBALIS) WITH ATIPAMEZOLE

摘要

The reversal of epidural xylazine, induced with IV atipamezole was evaluated in 15 buffaloes. Atipamezole at different dose rates (5, 10 and 15 μg/kg) injected 30 minutes after epidural xylazine provoked visible signs of arousal shortly after inection in all buffaloes without any side effects. The mean arousal times were 4.8±0.84 min, 2.4±0.24 min and 2.0±0.00 min while the mean total recovery times were 61.0±2.6 min, 33.0±3.7 min and 32.0±4.3 min following doses of 5, 10 and 15 μg/kg atipamezole respectively. The heart, respiratory and ruminal rates were mildly influenced. Overall, the IV atipamezole at a dose rate of 10 μg/kg was found effective and satisfactory for reversing the analgesic, sedative and cardiopulmonary depression effects induced by epidural xylazine administration in buffaloes.