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Is expected substance type associated with timing of drug checking service utilization?: A cross-sectional study

机译:预期与药物检查服务利用时机的物质类型有关吗?:横断面研究

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Drug checking is a harm reduction intervention aiming to reduce substance use-related risks by improving drug user knowledge of the composition of unregulated drugs. With increasing fears of fentanyl adulteration in unregulated drugs, this study sought to examine whether the expected type of drug checked (stimulant vs. opioid) was associated with timing of drug checking service utilization (pre-consumption vs. post-consumption). Data were derived from drug checking sites in British Columbia between October 31, 2017 and December 31, 2019. Pearson’s Chi-square test was used to examine the relationship between expected sample type (stimulant vs. opioid) and timing of service utilization. Odds ratios (OR) were calculated to assess the strength of this relationship. The Mantel–Haenszel (MH) test was used to adjust for service location. A total of 3561 unique stimulant and opioid samples were eligible for inclusion, including 691 (19.40%) stimulant samples; and 2222 (62.40%) samples that were tested pre-consumption. Results indicated a positive association between testing stimulant samples and testing pre-consumption (OR?=?1.45; 95% CI 1.21–1.73). Regions outside of the epicenter of the province’s drug scene showed a stronger association with testing pre-consumption (ORMH?=?2.33; 95% CI 1.51–3.56) than inside the epicenter (ORMH?=?1.33; 95% CI 1.09–1.63). Stimulant samples were more likely to be checked pre-consumption as compared with opioid samples, and stimulant samples were more likely to be tested pre-consumption in regions outside the epicenter of the province’s drug scene. This pattern may reflect a concern for fentanyl-adulterated stimulant drugs.
机译:药物检查是一种伤害减少干预,其旨在通过改善药物用户知识来减少物质使用相关的风险,从而改善未调节药物组成的药物。随着芬洲酰泛掺杂的恐惧在未经调节的药物中,该研究试图检查检查的预期类型的​​药物(兴奋剂与阿片类药物)是否与药物检查服务利用的时间相关(消费预付款)。 2017年10月31日至2019年12月31日之间的不列颠哥伦比亚省的药物检查站点来自Pearson的Chi-Square试验,用于检查预期样品类型(兴奋剂与阿片类药物)之间的关系和服务利用时间。计算赔率比(或)以评估这种关系的强度。 Mantel-Haenszel(MH)测试用于调整服务位置。共有3561个独特的兴奋剂和阿片类药物有资格包含,包括691(19.40%)兴奋剂样品;和2222(62.40%)测试预用的样品。结果表明测试兴奋剂样品和测试预消耗(或?= 1.45; 95%CI 1.21-1.73)之间的阳性关联。该省的震中外的地区的药物场景显示出与测试预消费(OrmH?= 2.33; 95%CI 1.51-3.56)的更强的关联(Ormh?=?1.33; 95%CI 1.09-1.63 )。与阿片样品样品相比,更容易检查刺激剂样品,并且与阿片样品样品相比,兴奋剂样品更容易在全省药物场景的震中以外的地区进行预消耗。该图案可以反映芬太尼掺杂的兴奋剂药物的担忧。

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