Vitamin C and corticosteroids in viral pneumonia

摘要

The current coronavirus disease 2019 (COVID-19) pandemic has re-ignited interest in using adjunctive agents—including corticosteroids and vitamin C—to attenuate the severity of viral pneumonia and acute lung injury [1,2]. Although the efficacy of dexamethasone on COVID-19 seems convincing, the role of corticosteroids with and without vitamin C in other viral pneumonia remains contentious and unclear. We hypothesised that high dose intravenous vitamin C (6 g/day) used in conjunction with corticosteroids could improve oxygenation in non–COVID-19 viral pneumonia.