Effects of radiotherapy in patients with nasopharyngeal carcinoma under continuous-discrete mixed mathematical model and comparison on the fungal and pathogen infection indexes before and after nutritional supplementation

摘要

The study aimed to explore the effects of radiotherapy on nasopharyngeal carcinoma (NPC) patients before and after nutritional supplementation, and the correlation between nutritional supplementation and infections, using continuous-discrete mixed mathematical model. Specifically, 398 NPC patients were selected based on information and health data. They all accepted radiation therapy, and enteral nutrition was provided through nasal feeding during the radiotherapy. Then, nutritional indicators, and infections were compared before and after nutritional supplementation. The results showed that, the radio-sensitivity coefficient and the age of tumor cells affected radiotherapy effects. After nutritional supplementation, the patient's Hemoglobin (Hb) was 139.26?±?12.87?g/L, the serum albumin (ALB) was 45.65?±?3.84?g/ L, the Lymphocyte (LYM) was 1.96?±?0.68 (×109/L), and the Body Mass Index (BMI) was 26.12?±?2.63 (kg/m2). Among them, Hb, LYM, and BMI were notably different from those before treatment (P?