ASSOCIATION BETWEEN RELATIVE ESTIMATED GLOMERULAR FILTRATION RATE CHANGES AND DAYS OUT OF THE HOME AND COST OUTCOMES IN PATIENTS WITH TYPE 2 DIABETES

摘要

Introduction: A $40% relative decline in estimated glomerular filtra- tion rate (eGFR) has been supported for use as a surrogate endpoint for clinical outcomes. However, the associations between this change and resulting days that a patient spends out of their primary ambulatory residence (e.g., during inpatient admissions and nursing facility stays) and cost outcomes are limited. The purpose of this analysis was to evaluate the associations of relative changes in eGFR with days out of the home and with cost outcomes in patients with type 2 diabetes mellitus (T2DM).