PurposeTo present two cases of neonatal endophthalmitis with poor prognosis that were managed with primary evisceration.ObservationsCase 1 is a 27-weeks’ gestation neonate who developedPseudomonas aeruginosaendophthalmitis complicated by globe rupture. Case 2 describes a 34-weeks’ gestation neonate withSerratia marcescensendophthalmitis. Both patients had poor prognosis and thus underwent primary evisceration with good long-term cosmetic outcomes at 15 years and 17 months, respectively.Conclusions and ImportancePrimary evisceration should be considered in neonates with endophthalmitis with a poor prognosis and can result in good long-term cosmesis.
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