Evaluation of erectile dysfunction in the ageing men using colour Doppler sonography

摘要

Background:Erectile dysfunction (ED) is common among ageing men because of associated underlying risk factors which are peculiar to this category of patients. Endothelial dysfunction and replacement of cavernosal smooth muscles by collagen fibres are common in older men, making them prone to ED. It is either vasogenic, neurogenic, hormonal, cavernosal or psychogenic in origin, but vasogenic causes are the commonest. This study was aimed at establishing vasogenic causes among patients being evaluated for ED using Doppler ultrasound as this category of ED is amenable to either medical and/or surgical treatment.MethodsThe study was conducted from July 2015 to January, 2017 at Federal Medical Centre Abuja. Nineteen consecutive patients with clinical diagnosis of erectile dysfunction were evaluated with Doppler ultrasound scan using a high-frequency linear array transducer. The penile scan was done before and after intracavernosal injection of 20?μg of Prostaglandin E₁ (PGE₁). B-mode scan of the penis was done prior to intracavernosal injection of PGE₁, and the spectral waveforms as well as peak systolic velocity (PSV) of the CA were recorded at 5?min interval, from 5 to 50?min post-intracavernosal injection of PGE₁, using angle of insoation?≤?60°.ResultsThe age range of the patients was fifty to sixty-six years (mean: 57.4?±?4.3?years), while the PSV of CA varied between 21.4 and 104.4?cm/s (mean: 46.2?±?19.2) among the entire patients, between 21.4 and 22.3?cm/s (mean: 21.9?±?0.7) among patients with arteriogenic ED, and between 25.0 and 74.9?cm/s (mean: 45.0?±?15.5) among those with venogenic ED. Arteriogenic ED was found in two patients (10.6%), while venogenic ED was observed in seven patients, which constituted 36.8% of the entire research participants. None had Peyronie’s disease, penile fracture, penile tumour or mixed arteriogenic and venogenic ED.Conclusion47.4% of the patients had vasogenic ED and venogenic ED was more common than arterioegenic ED in the age range considered. This categorization of ED with Doppler study is imperative before initiating therapy as treatment protocol for vasogenic ED is aetiologic specific.