Glycolysis and gluconeogenesis: A teaching view

摘要

I read with interest the recent review “Tracking the carbonssupplying gluconeogenesis” by Ankit M. Shah and Fredric E.Wondisford (1). The figures are clear, and they are a goodteaching source. Nevertheless, I note some potential teachingissues as well as offer additional suggestions. It is well knownand it is explained to our students that there are three reactions of glycolysis that are essentially irreversible: hexokinase, phosphofrutokinase-1, and pyruvate kinase. Thus, Iwould like to observe in relation to Figure 1 that.