Study on Assessment of Thyroid Status among Critically Ill Patients Admitted in a Tertiary Care Hospital

摘要

Introduction: Any acute severe illness can cause abnormalities of circulating TSHor thyroid hormone levels in the absence of underlying thyroid disease.AIM: To assess thyroid status among critically ill patients admitted in a tertiarycare hospital.Material & Methods: A hospital based cross sectional study was done among100 critically ill patients admitted to Katuri Medical College and Hospital,Chinakondrupadu, Guntur. All critically ill patients aged above 18 years admittedto Intensive Care Unit, Emergency ward and patients suffering from Acute renalfailure, Acute Respiratory failure, Congestive cardiac failure, Diabetic ketoacidosis,Septicemia and Advanced HIV infection were included. 3ml of early morningsample containing plain clotted blood were collected and sent for T3, T4, TSHestimation. The hormone estimation was done by chemiluminescence assay.Results: In the study, of 100 critically ill patients out of which 16 patients hadacute renal failure, 18 patients had acute respiratory failure, 18 patients hadcongestive Cardiac failure, 16 patients had Diabetic ketoacidosis, 18 patients hadSepsis and 14 patients had Advanced HIV. Among 100 patients, 60% had low T3,26% had low T4, 10% had high T4 and 4% had low TSH.Conclusions: Abnormalities in thyroid function were more common in criticallyill non thyroidal illness patients.