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Estimated blood loss and anemia predict transfusion after total shoulder arthroplasty: a retrospective cohort study

机译:估计失血和贫血预测总肩部关节置换术后的输血:回顾性队列研究

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Background Reported blood transfusion rates after total shoulder arthroplasty (TSA) range from 4.5% to 43%, and reported risk factors include race, female sex, prosthesis type (reverse), revision, age, anemia, low preoperative hemoglobin, and number of comorbidities. The purpose of this study was to develop a predictive model for transfusion in anatomic/hemi and reverse shoulder arthroplasty patients and to estimate the transfusion rate in a community hospital setting. Methods A retrospective cohort of 265 shoulder arthroplasties (79 anatomic, 182 reverse, and 4 hemiarthroplasties) performed consecutively by 1 surgeon at 1 institution from May 2013 to May 2016 was assembled. Two patients were excluded for insufficient data, leaving 263 patients for analysis. Sensitivity, specificity, area under the curve, and cut points using estimated blood loss (EBL), history of anemia, and preoperative hemoglobin level were calculated, based on a logistic regression model. Results The overall transfusion rate was 2.3% (6/265). Higher EBL ( P ?= .003), lower preoperative hemoglobin level ( P ?= .030), and history of anemia ( P ?= .088) were predictive of transfusion with a sensitivity of 80.0% and a specificity of 99.6%. In this cohort, patients with a history of anemia had transfusion risk when an EBL of ≥300 mL was combined with a preoperative hemoglobin level 10.9, resulting in a sensitivity of 1.0 and a specificity of 0.96. Factors associated with transfusion in univariate models included arthroplasty for fracture ( P .001), cemented stem ( P .001), length of stay ( P .001), EBL ( P .001), operative time ( P .001), and preoperative hemoglobin ( P ?= .004) and hematocrit levels ( P ?= .004). Conclusion Patients with a history of anemia, a preoperative hemoglobin level 10.9, and an intraoperative EBL ≥300 mL are at high risk for transfusion after TSA.
机译:背景技术报告的肩部关节置换术(TSA)的血液输血率从4.5%到43%,报告的风险因素包括种族,女性性别,假体类型(反向),修订,年龄,贫血,低术前血红蛋白和合并症数量。本研究的目的是开发一种在解剖学/半期和逆转肩关节成形术患者中输血的预测模型,并估算社区医院环境中的输血率。方法采用2013年5月至2016年5月的1个Surgeon在1个外科医生连续1次外科医生连续1次肩部关节塑料(79个解剖学,182次逆转录和4个半序塑料)的回顾性队列。两名患者被排除在不足的数据中,留下263名患者进行分析。基于逻辑回归模型,计算了使用估计失血(EBL),贫血病史和术前血红蛋白水平的曲线下的敏感性,特异性,切割点。结果总输血率为2.3%(6/265)。更高的EBL(p?= .003),较低的术前血红蛋白水平(p?= .030),贫血史(p?= .088)预测输血,敏感性为80.0%,特异性为99.6%。在这种队列中,当≥300ml的EBL与术前血红蛋白水平<10.9结合时,患有贫血史的患者具有输血风险,导致1.0的灵敏度和0.96的特异性。与单变量模型中输血相关的因素包括骨折的关节成形术(P <.001),硬质茎干(P <.001),留守长度(P <.001),EBL(P <.001),操作时间(P < .001),术前血红蛋白(p?= .004)和血细胞比容水平(p?= .004)。结论贫血病史患者,术前血红蛋白水平<10.9和术中EBL≥300mL在TSA后输血的高风险。

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