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The Novel Coronavirus 2019 Epidemic and the Kidneys

机译:新型冠状病毒2019年流行病和肾脏

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The Severe Acute Respiratory Syndrome Coronavirus 2 is a recent disease that originated in China by the end of 2019. The origins of the disease can be traced to bats, but it has been transmitted to humans, and the inter human transmission is particularly rampant which has led to a pandemic of unseen proportions.The organ principally involved is the lungs, and severe pneumonia with lack of oxygen leads to fatalities.The aim of this review was to study the involvement of the kidneys with regard to COVID-19 infection and how the disease may affect people on hemodialysis or those who have undergone a kidney transplant.Indeed, the virus, in addition to the lungs, may affect other vascularized organs to a common receptor on lung epithelium and the endothelium of any organ.The kidney, which has a large endothelium surface, is affected, and COVID-19 may lead to acute renal failure.On the other hand, the virus may easily spread among people who are on hemodialysis three times a week. People on hemodialysis may have low immunity, and the virus may have dangerous effects on such people.Finally, renal transplant patients may be easily affected, and the virus may have severe consequences, even death.We will summarize the principal prophylactic measures to be adopted and the therapeutic measures available. Clearly due to the recent occurrence of the pandemic the majority these measures lack a basis in evidence-based medicine and only highlight the efforts to limit COVID-19 induced damage.
机译:严重的急性呼吸综合征冠状病毒2是最近在2019年底之前发起的疾病。该疾病的起源可以追溯到蝙蝠,但它已被传播给人类,并且人类跨人类传播特别猖獗导致了一个看不见的比例。主要涉及的器官是肺部,缺氧的严重肺炎导致死亡。本综述的目的是研究肾脏对Covid-19感染方面的参与和如何疾病可能影响血液透析或经过肾移植的人的人。此外,病毒除了肺外,病毒可能会影响其他血管化器官对肺上皮的共同受体和任何器官的内皮。肾脏,具有较大的内皮表面受到影响,Covid-19可能导致急性肾功能衰竭。另一方面,病毒可能在每周三次上血液透析的人群中容易蔓延。血液透析的人可能具有低免疫力,病毒可能对这些人产生危险的影响。最后,肾移植患者可能很容易受到影响,并且病毒可能具有严重的后果,甚至死亡。我们将总结待采用的主要预防措施和可用的治疗措施。显然,由于最近发生的大流行发生了大多数这些措施缺乏循证医学的基础,只突出了限制Covid-19诱导损伤的努力。

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