Objective Vitamin D has been widely studied as a mediator of the immune response, becoming evident the prevalence of hypovitaminosis D in patients with Crohn's disease. This work aims at evaluating the serum levels of vitamin D in patients suffering from Crohn's disease in a southeast region of Brazil. Methods It is a prospective study, with statistical analysis of the values of serum vitamin D measured between April 2014 and April 2015 in patients with Crohn's disease. Individuals with mild anal complaints, without any colorectal involvement, comprised the control group. Results One hundred and four patients whose average age was 40.6 years were evaluated, being 56 (53.8%) female and 48 (46.2%) male. The average serum vitamin D level was 21.6 ng/mL, with standard deviation 13.85. The control group was comprised by 66 individuals, whose average age was 48.9 years. With 38 (57.6%) female and 28 (42.4%) male. In this group the average serum vitamin D level was 40.9 ng/mL. Statistical significance was demonstrated with p < 0.0001. Conclusion There was high prevalence of hypovitaminosis D in patients with Chron's disease, when compared to the control group. Hypovitaminosis D was not evidenced in patients in the latter group.
展开▼
机译：目标维生素D已被广泛研究作为免疫应答的介质，变得明显，克罗恩病患者的下钙胺素D的患病率。这项工作旨在评估患者在巴西东南部地区患有克罗恩病的患者维生素D血清水平。方法是一项潜在的研究，统计分析2014年4月至2015年4月至2015年4月患者患有克罗恩病的患者。具有轻度肛门投诉的个体，没有任何结直肠癌，包括对照组。结果评估平均年龄为40.6岁的患者，是56（53.8％）女性和48名（46.2％）男性。平均血清维生素D水平为21.6 ng / ml，标准偏差13.85。对照组由66个个体组成，其平均年龄为48.9岁。 38（57.6％）女性和28名（42.4％）男性。在该组中，平均血清维生素D水平为40.9ng / ml。 P <0.0001证明了统计学意义。结论与对照组相比，血红素疾病患者患者患有高血吸虫病患病率。后一组患者没有证明下钙胺素D没有证明。
展开▼
