In each duplication cycle, daughter centrioles grow to the same length as their mothers. Which mechanisms regulate this fidelity to maintain centriole length is not known. In this issue, Aydogan et al. (2018. J. Cell Biol. https://doi.org/10.1083/jcb.201801014) report a novel role for Polo-like kinase 4 (Plk4). They found that Plk4 functions in a homeostatic manner to balance growth rate and growth period to set the final centriole size.
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机译:在每种复制循环中,女儿厘莫瑞斯长的长度与母亲一起长度。哪些机制调节这种保真度以维持沿厘米长度不知道。在这个问题中,Aydogan等人。 (2018. J. Cell Biol。https://doi.org/10.1083/jcb.2018014)报告对Polo样激酶4(PLK4)的新颖作用。他们发现PLK4以稳态方式起作用,以平衡增长率和生长期,以设定最终的离心尺寸。
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