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Personalized setting of plan parameters using feasibility dose volume histogram for auto‐planning in Pinnacle system

机译:使用可行性剂量块直方图进行Pinnacle系统的自动规划的Plan参数的个性化设置

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Purpose The personalized setting of plan parameters in the Auto‐Planning module of the Pinnacle treatment planning system (TPS) using the PlanIQ feasibility tool was evaluated for lung cancer conventional fractionated radiotherapy (CFRT). Materials and method We reviewed the records of ten patients with lung cancer who were treated with volumetric modulated arc therapy (VMAT). Three plans were designed for each patient: the clinically accepted manual plan (MP) and two automatic plans including one generated using the generic plan parameters in technique script (AP1) and the other generated using personalized plan parameters derived based on feasibility dose volume histogram (FDVH) in PlanIQ (AP2). The plans were assessed according to the dosimetric parameters, monitor units, and planning time. A plan quality metric (PQM) was defined according to the clinical requirements for plan assessment. Results AP2 achieved better lung sparing than AP1 and MP. The PQM value of AP2 (52.5?±?14.3) was higher than those of AP1 (49.2?±?16.2) and MP (44.8?±?16.9) with P ?0.05. The monitor units of AP2 (585.9?±?142.9?MU) was higher than that of AP1 (511.1?±?136.5?MU) and lower than that of MP (632.8?±?143.8?MU) with p??0.05. The planning time of AP2 (33.2?±?4.8?min) was slightly higher than that of AP1 (28.2?±?4.0?min) and substantially lower than that of MP (72.9?±?28.5?min) with P ?0.05. Conclusions The Auto‐Planning module of the Pinnacle system using personalized plan parameters suggested by the PlanIQ Feasibility tool provides superior quality for lung cancer plans, especially in terms of lung sparing. The time consumption of Auto‐Planning was slightly higher with the personalized parameters compared to that with the generic parameters, but significantly lower than that for the manual plan.
机译:目的,评估使用Planiq可行性工具的Pinnacle治疗计划系统(TPS)的自动规划模块中规划参数的个性化设置,用于肺癌常规分级放疗(CFRT)。材料和方法我们审查了10例肺癌患者的记录,该肺癌被体积调制的电弧疗法(VMAT)处理。为每位患者设计了三项计划:临床上接受的手动计划(MP)和两个自动计划,包括使用技术脚本(AP1)中的通用计划参数生成的手动计划和使用基于可行性剂量卷直方图导出的个性化计划参数生成的另一个生成的计划( FDVH)在Planiq(AP2)中。根据剂量分析,监测单位和规划时间评估计划。计划质量指标(PQM)是根据计划评估的临床要求定义的。结果AP2比AP1和MP实现更好的肺部备用。 AP2的PQM值(52.5?±14.3)高于AP1(49.2?±16.2)和MP(44.8→α16.9),P <0.05。 AP2的监测单元(585.9?±142.9μ)高于AP1(511.1〜±136.5·mu),低于MP的(632.8?±143.8亩),p?<?0.05 。 AP2的规划时间(33.2?±4.8?min)略高于AP1(28.2≤x≤4.0≤min),并且具有P <α的MP(72.9?±28.5〜5×28.5〜5×28.5Ω··28.5℃)。 0.05。结论使用Planiq可行性工具建议的个性化计划参数的Pinnacle系统的自动计划模块为肺癌计划提供了卓越的品质,尤其是肺癌备件。与具有通用参数相比,个性化参数的时间略高,自动规划的时间略高,但与通用参数相比,但显着低于手动计划的参数。

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