Advances in anti-tumor mechanism and clinical application of Astragalus polysaccharides

摘要

Highlights Astragalus polysaccharide is one of the main components of astragalus. It is a natural extract with a variety of effects and has a specific therapeutic effect on patients with malignant tumors. Astragalus polysaccharides can exert antitumor effects in a variety of ways, such as reducing the side effects of radiation therapy, chemotherapy, immunotherapy and targeted therapy, and also play a synergistic role in combination therapy. Astragalus polysaccharide has shown sound anti-tumor effects, and its mechanism is related to directly inhibiting the growth of tumor cells, promoting apoptosis, inhibiting tumor angiogenesis and enhancing cellular immunity. Abstract Astragalus polysaccharide has the beneficial effect of Qi-deficiency, and it also has several anti-tumor mechanisms, including pharmacological actions and clinical functions. Through literature review, this work concluded anti-tumor mechanism and clinical application of astragalus polysaccharide, which was of considerable significance to expand and optimize its anti-tumor function and clinical application.