ASSOCIATION OF CHRONIC PERIODONTITIS WITH CARDIOVASCULAR DISEASES

摘要

Aim of this review was to publish a brief literature review?based on recent studies, highlighting the association of chronic periodontitis with cardiovascular ailments. A comprehensive literature study was completed by using two databases and one search engine namely: ‘MEDLINE’, ‘PUBMED’ and ‘GOOGLE SCHOLAR’ respectively. The referenced literature comprised of observational and case studies, systematic reviews, randomized control trials and short communications. Etiological pathophysiology, significance of the association and common mediators of periodontitis as well as cardiovascular diseases were briefly described. Epidemiological studies declared the causative role of chronic periodontitis in cardiovascular pathologies. Periodontal flora and its toxins have been linked to atherosclerosis. Common immune-inflammatory mediators possessed a significant role in the pathogenesis of heart-vascular pathologies. Periodontitis has been considered as an independent risk factor for the initiation and aggravation of cardiovascular ailments. However, by using primary periodontal measures, the chances of periodontitis can be minimized and the risk for cardiovascular diseases can be controlled.