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Incidence of Contrast-Induced Nephropathy after Coronary Procedures in the United Arab Emirates: A Single-Center Study

机译:阿拉伯联合酋长国冠状动脉手术后对比引起的肾病发病率:单中心研究

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Contrast-induced nephropathy (CIN) is a major cause of morbidity and mortality in patients undergoing coronary procedures. The reported incidence of CIN ranges from ~3% to 30%. The profile of patients undergoing coronary procedures in the United Arab Emirates (UAE) differs from those included in published reports of CIN, and the incidence of CIN after coronary procedures in the UAE remains unknown. We conducted a retrospective analysis of all adult patients who underwent coronary procedures at a large tertiary care facility in the UAE in 2013–2014. Patients on dialysis or missing creatinine values were excluded. CIN was defined as an increase of creatinine of ≥44 μmol/L within 48–72 h after coronary procedures. Most patients (84.8%) underwent coronary procedures for urgent/emergent indications. The incidence of CIN was 44 out of 1010 (4.35%), with 17 out of 44 (38%) of CIN patients requiring dialysis. After adjusting for baseline differences, older patients, use of angiotensin-converting enzyme inhibitors, and oxygen use during the procedure were associated with a 20.6% increased risk of development of CIN. The risk of in-hospital mortality was significantly higher in the CIN group (29.5% vs. 1.8%).
机译:对比诱导的肾病(CIN)是接受冠状动脉手术患者的发病率和死亡率的主要原因。报告的CIN的发病率从〜3%到30%。接受阿拉伯联合酋长国(阿联酋)冠状动脉患者的概况与Cin的公布报告中包含的患者不同,而阿联酋冠状动脉内的CIN发生率仍然未知。我们对2013 - 2014年阿联酋大三级护理设施进行了冠状动脉手术的所有成年患者进行了回顾性分析。排除透析或缺少肌酐值的患者。 CIN被定义为冠状动脉手术后48-72小时内≥44μmol/ L的肌酐的增加。大多数患者(84.8%)接受迫切/紧急症的冠状动脉手术。 CIN的发病率为1010(4.35%),44个(38%)的诊断为17例(38%)的患者,其中44例(38%)。调整基线差异后,较老的患者,使用血管紧张素转化酶抑制剂的使用和过程中的氧气使用与增加的CIN发育风险增加20.6%。 CIN组在医院内死亡率的风险明显高(29.5%与1.8%)。

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