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Protective Effects of Fullerene C60 Nanoparticles and Virgin Olive Oil against Genotoxicity Induced by Cyclophosphamide in Rats

机译:富勒烯C60纳米粒子和初榨橄榄油对大鼠环磷酰胺诱导遗治毒性的保护作用

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摘要

The potential effects of the fullerene C60 nanoparticle (C60) as well as virgin olive oil (VOO) against the cyclophosphamide- (CP-) induced cytotoxic and mutagenic effects were evaluated by two main methods molecular intersimple sequence repeat (ISSR) assay and cytogenetic biomarkers. Thirty adult male rats were divided to five groups (control, CP, C60, CP 
机译:通过两种主要方法分子间隔序列重复(ISSR)测定和细胞遗传学生物标志物,评估富勒烯C60纳米粒子(C60)以及乙醛橄榄油(voO)对环磷酰胺(CP-)诱导的细胞毒性和致突毒性效应的潜在影响。三十个成年雄性大鼠分为五组(对照,CP,C60,CP

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