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Operative Versus Nonoperative Treatment of Acute Achilles Tendon Ruptures: A Pilot Economic Decision Analysis

机译:手术与急性阿基里斯肌腱破裂的非手术治疗:试验经济决策分析

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Background: The operative treatment of Achilles tendon ruptures has been associated with lower rerupture rates and better function but also a risk of surgery-related complications compared with nonoperative treatment, which may provide improved outcomes with accelerated rehabilitation protocols. However, economic decision analyses integrating the updated costs of both treatment options are limited in the literature. Purpose: To compare the cost-effectiveness of operative and nonoperative treatment of acute Achilles tendon tears. Study Design: Economic and decision analysis; Level of evidence, 2. Methods: An economic decision model was built to assess the cost-utility ratio (CUR) of open primary repair versus nonoperative treatment for acute Achilles tendon ruptures, based on direct costs from the practices of sports medicine and foot and ankle surgeons at a single tertiary academic center, with published outcome probabilities and patient utility data. Multiway sensitivity analyses were performed to reflect the range of data. Results: Nonoperative treatment was more cost-effective in the average scenario (nonoperative CUR, US$520; operative CUR, US$1995), but crossover occurred during the sensitivity analysis (nonoperative CUR range, US$224-US$2079; operative CUR range, US$789-US$8380). Operative treatment cost an extra average marginal CUR of US$1475 compared with nonoperative treatment, assuming uneventful healing in both treatment arms. The sensitivity analysis demonstrated a decreased marginal CUR of operative treatment when the outcome utility was maximized, and rerupture rates were minimized compared with nonoperative treatment. Conclusion: Nonoperative treatment was more cost-effective in average scenarios. Crossover indicated that open primary repair would be favorable for maximized outcome utility, such as that for young athletes or heavy laborers. The treatment decision for acute Achilles tendon ruptures should be individualized. These pilot results provide inferences for further longitudinal analyses incorporating future clinical evidence.
机译:背景:血管肌腱破裂的手术治疗与率较低的速率和更好的功能有关,而且与非手术治疗相比,手术相关并发症的风险,这可能提供加速康复方案的改善的结果。然而,经济决策分析整合两种治疗方案的更新成本在文献中有限。目的:比较急性阿基里斯肌腱撕裂的手术和非手术治疗的成本效益。研究设计:经济和决策分析;证据水平,2.方法:建立经济决策模型,以评估开放初级修复的成本效率(CUR)与急性Achilles肌腱破裂的非手术治疗,基于运动医学和脚的实践,在一个三级学术中心的脚踝外科医生,具有公布的结果概率和患者实用数据。进行多道灵敏度分析以反映数据范围。结果:非手术治疗在平均场景中更具成本效益(非专利,520美元;操作CUR,1995美元),但在敏感性分析期间发生了交叉(非专利CUR范围,US $ 224-US $ 2079;手术CUR范围,美国$ 789-US $ 8380)。与非手术治疗相比,手术治疗成本为1475美元的额外平均边际次数为1475美元,假设两个治疗臂中的愈合不败。敏感性分析表明,当结果效用最大化时,术后术治疗的边际冲突降低,与非手术治疗相比,率变得最小化。结论:在平均场景中,非手术治疗更具成本效益。交叉表明,开放的主要修复对于最大化的成果效用是有利的,例如年轻运动员或沉重劳动者。对急性血管肌腱破裂的治疗决定应该是个性化的。这些导频结果提供了进一步纵向分析的推论,包括未来的临床证据。

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