Validation of the Thai version of SARC-F, MSRA-7, and MSRA-5 questionnaires compared to AWGS 2019 and sarcopenia risks in older patients at a medical outpatient clinic

摘要

ObjectivesTo validate the Thai Strength, Assistance with walking, Rise from a chair, Climb stairs and Falls (SARC-F), and 2 Mini Sarcopenia Risk Assessment (MSRA-5, and MSRA-7) questionnaires for sarcopenia screening in older patients in the medical outpatient setting, and to assess the improvements of the diagnostic accuracy by adapting the parameters in the SARC-F, MSRA-7, and MSRA-5 questionnaires. Risk factors for sarcopenia are also investigated.MethodsThai SARC-F, MSRA-7, and MSRA-5 questionnaires were translated backwards and forwards. Content validity and test–retest reliability were analyzed. Reliability analysis was used for SARC-F, MSRA-7, and MSRA-5 scores to increase the sensitivity and specificity. The sensitivity, specificity, likelihood ratio, and area under the receiver operating characteristic curves (AUCs) were analyzed.ResultsThe prevalence of sarcopenia was 22.7% (65 of 286 patients). The sensitivity of the SARC-F, MSRA-7, and MSRA-5 questionnaires was 21.5%, 72.3%, and 61.5%, respectively. The specificity was 93.7%, 43%, and 67.4%, respectively. The AUCs were 0.58, 0.58, and 0.65, respectively. After weighting and adjusting the scores for the least responded-to items of the MSRA-5, the sensitivity increased to 82.6%, specificity to 43.4%, and AUC to 0.65. Multivariate analysis showed that the associated factors of sarcopenia were age [odds ratio (OR)?=?5.92], body mass index?