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Exploring The Current Management Idiopathic Intracranial Hypertension, And Understanding The Role Of Dural Venous Sinus Stenting

机译:探索目前的管理发作性颅内高血压,了解Dural静脉窦房位的作用

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Idiopathic Intracranial Hypertension (IIH) is a debilitating disorder characterised by raised intracranial pressure (ICP), papilloedema with the potential risk of permanent visual loss, and headaches that are profoundly disabling and reduce the quality of life. The first consensus guidelines have been published on investigation and management of adult IIH and one key area of uncertainty is the utility of dural venous sinus stenting for the management of headache and visual loss. There are an increasing number of series published and to help understand the successes and complications. During a patient physician priority setting, the understanding of the best type of intervention to treat IIH was assigned to the top 10 of most desired research questions for the disease. Ultimately randomised clinical trials (RCTs) in neurovascular stenting for IIH would be instructive, as the literature to date may suffer from publication bias. Due to the increasing incidence of IIH, there is no better time to systematically investigate interventions that may reverse the disease process and achieve remission. In this review we discuss the pathophysiology of IIH in relation to venous sinus stenosis, the role of venous sinus stenting with a review of the relevant literature, the advantages and disadvantages of stenting compared with other surgical interventions, and the future of stenting in the treatment of IIH.
机译:特发性颅内高血压(IIH)是一种衰弱的疾病,其特征在于引起颅内压(ICP),乳头对肿瘤症,具有永久性视力损失的潜在风险,以及深刻禁用和降低生活质量的头痛。第一次共识指南已发表于成年人IIH的调查和管理,一个关键不确定性的关键领域是硬脑膜窦弥补痛苦和视力损失的效用。越来越多的系列发布,并帮助了解成功和并发症。在患者的医生优先级设置期间,对治疗IIH的最佳干预类型的理解被分配给该疾病最期望的研究问题的前10名。最终在神经血管支架中的随机临床试验(RCT)将是有益的,因为迄今为止的文献可能遭受出版物偏见。由于IIH的发病率越来越高,没有更好的时间来系统地研究可能扭转疾病过程并实现缓解的干预措施。在本文中,我们讨论了IIH与静脉窦狭窄的病理生理学,静脉窦房位的作用与审查相关文献,与其他外科干预相比,支架的优势和缺点,以及治疗中支架的未来IIH。

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