Linear and non-linear EEG analyses before and after psychosis in patients with epilepsy

摘要

To investigate the linearity and nonlinearity of EEGs before and after psychosis in patients withepilepsy, continuous EEGs before and after psychosis of five patients who developed epilepticpsychosis were examined. The continuous EEGs of eight patients without psychosis were used ascontrols. EEGs were analyzed by Fourier transform for the frequency bands of delta, theta, alpha,and beta aslinear indices and by Sample entropy (SampEn) as a nonlinear index. Significantchanges were seen in SampEn before vs after psychosis at bilateral frontal and frontal-anteriortemporal regions. Significant differences in SampEn between the before psychosis group and thecontrol group were found at the right frontal and frontal-anterior temporal regions. In patientswith epilepsy, SampEn may not only decrease in the right frontal and frontal-anterior temporalregions before psychosis, but it may also increase in the frontal and frontal-temporal regions dur-ing psychosis. EEG complexity may be useful to investigate the pathophysiological associationbetween epilepsy and psychosis.