ANTIIMPLANTATION ACTIVITY OF THE METHANOLIC EXTRACT OF CORDIA DICHOTOMA LAM. BARK IN RATS

摘要

In the present study, antiimplantation activity of methanolic extract of Cordia dichotoma Lam. bark was evaluated. The methanolic extract of bark of Cordia dichotoma showed significant antiimplantation activity. Pretreatment with methanolic extract showed significant inhibition of number of implant site at a dose of 100-mg/kg-body weight. There was no change in ovulation; hence the antiimplantation activity observed in the present study with Cordia dichotoma bark can be attributed largely to its inhibition of number of implants. However, an investigation of ?the antiimplantation activity showed ?no increase in body weight or uterine content of blood glucose, cholesterol and triglyceride levels when compared with control group.