Changing epidemiology of neovascular glaucoma from 2002 to 2012 at King Khaled Eye Specialist Hospital, Saudi Arabia

摘要

Purpose: The aim is to present the incidence and determinants of neovascular glaucoma (NVG) in Saudi Arabia. Methods: A retrospective review of NVG cases (2002–2012) was included to estimate the incidence. The determinants included gender, age, comorbidities, lens status, type of NVG, and visual acuity on presentation. The impact of antiangiogenic therapy on NVG incidence was studied. Results: We studied 597 eyes with NVG. The incidence was 6.6/10,000. It declined from 13/10,000 in 2008–0.1/10,000 in 2012 (P 7%). Visual acuity was 20/20–20/40 in 14 (2%), 20/50–20/200 in 79 (13%), 20/200–20/400 in 456 (76%), and 0.8 in 86 (14%) eyes. During the early period (2002–2007) and later period (2008–2012), CD ratio (χ2 = 4, P = 0.09) and anterior chamber angle (P = 0.8) were not different. The presence of NVG in contralateral eye (OR = 0.8, P = 0.3) in both periods was similar. Conclusions: NVG was associated with diabetes in a very large proportion of patients. It was significantly associated with males, and with poor glycemic control and poor vision at presentation. The incidence of NVG declined after the introduction of intravitreal bevacizumab.