Risk factor and clinicopathologic characteristics of synchronous multiple early gastric neoplasms for surgical treatment

摘要

We found the main pathological type of the single neoplasia group is early gastric adenocarcinoma, while the early gastric adenocarcinoma and HGIN were almost the same numbers of syn- chronous neoplasia lesions. This result is distinct from the previous study.’ We speculate that the incidence of intestinal metaplasia and chronic atrophic gastritis in the synchronous neoplasia group is significantly higher than that in the single group, resulting in a more clinical symptom than the single group. Taken together, our work demonstrated that male sex, chronic atrophy gastritis, and IM are independent predictive risk factors of SMEGC. The main and minor lesions of SMEGC share some similar clinicopathologic characteristics. Therefore, the endoscopic physicians need a more meticulous endoscopic examination and find the possibility of SMEGC considering the understanding of the characteristic of the main and minor lesions.