Visual function improvement using photocromic and selective blue-violet light filtering spectacle lenses in patients affected by retinal diseases

摘要

Background To evaluate functional visual parameters using photocromic and selective blue-violet light filtering spectacle lenses in patients affected by central or peripheral scotoma due to retinal diseases. Sixty patients were enrolled in this study: 30 patients affected by central scotoma, group 1, and 30 affected by peripheral scotoma, group 2. Black on White Best Corrected Visual Acuity (BW-BCVA), White on Black Best Corrected Visual Acuity (WB-BCVA), Mars Contrast Sensitivity (CS) and a Glare Test (GT) were performed to all patients. Test results with blue-violet filter, a short-pass yellow filter and with no filters were compared. Results All scores from test results increased significantly with blue-violet filters for all patients. The mean BW-BCVA increased from 0.30?±?0.20 to 0.36?±?0.21 decimals in group 1 and from 0.44?±?0.22 to 0.51?±?0.23 decimals in group 2 (Mean?±?SD, p The mean WB-BCVA increased from 0.31?±?0.19 to 0.38?±?0.23 decimals in group 1 and from 0.46?±?0.20 to 0.56?±?0.22 decimals in group 2 (Mean?±?SD, p The letter count for the CS test increased from 26.7?±?7.9 to 30.06?±?7.8 in group 1 (Mean?±?SD, p =?0.0005) and from 31.5?±?7.6 to 33.72?±?7.3 in group 2 (Mean?±?SD, p =?0.031). GT was significantly reduced: the letter count increased from 20.93?±?5.42 to 22.82?±?4.93 in group 1 (Mean?±?SD, p p Higher scores were recorded with the Blue filter compared to Yellow filter in all tests ( p No significant differences in any test results could be detected between the Yellow filter and the No filter condition. Conclusions The use of a combination of photocromic lens with a selective blue-violet light filter showed functional benefit in all evaluated patients.