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首页> 外文期刊>BMC Cardiovascular Disorders >Predictive value of neutrophil to lymphocyte ratio in patients with acute ST segment elevation myocardial infarction after percutaneous coronary intervention: a meta-analysis
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Predictive value of neutrophil to lymphocyte ratio in patients with acute ST segment elevation myocardial infarction after percutaneous coronary intervention: a meta-analysis

机译:急性ST段升高患者中性粒细胞与淋巴细胞比率的预测值急性ST段抬高心肌梗死后经皮冠状动脉介入后:荟萃分析

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The neutrophil to lymphocyte ratio (NLR) is an indicator of systemic inflammation and a prognostic marker in patients with acute coronary syndrome (ACS). This study aims to investigate the value of NLR to predict the in-hospital and long-term prognosis in patients with ST segment elevation myocardial infarction (STEMI) after percutaneous coronary intervention (PCI) by meta-analysis. The studies related to the prognosis of NLR and STEMI patients published in the Pubmed, Embase, and Ovid databases before June 2017 were retrieved. The relevant data were extracted. Review Manager Version 5.3 was used for meta-analysis. A total of 14 studies of 10,245 patients with STEMI after PCI were included. A significant difference was observed for mortality (P?
机译:中性粒细胞与淋巴细胞比(NLR)是急性冠状动脉综合征(ACS)患者的全身炎症和预后标志物的指标。本研究旨在探讨NLR在经皮冠状动脉介入(PCI)后ST段抬高心肌梗死(STEMI)通过META分析后预测患者的内部医院和长期预后。检索到2017年6月之前发表于Pubmed,Embase和Ovid数据库中发表的NLR和STEMI患者预后的研究。提取相关数据。 Review Manager 5.3版用于Meta-Analysis。包括PCI后的10,245名患者的14项研究。对死亡率观察到显着差异(p?<〜0.001;相对风险(RR)3.32; 95%置信区间(CI)2.45-4.49),医院心脏病死亡率(P?<〜0.001; RR 3.22; 95%CI 2.25 -4.60),所有死亡率(p?<〜0.001; rr 3.23; 95%ci 2.28-4.57),主要不良心血管事件(MACE)(p?<0.001; RR 2.00; 95%CI 1.62-2.46),在 - 血栓形成(p?<0.001; RR 2.72 95%CI 1.66-4.44),非常见心肌梗死(MI)(P?<〜0.001; RR 1.93; 95%CI 1.43-2.61),心绞痛(P?=? 0.007; rr 1.67; 95%ci 1.15-2.41),晚期心力衰竭(ahf)(p?<0.001; rr 1.81; 95%ci 1.48-2.21),心律失常(p?= 0.002; RR 1.38; 95% CI 1.13-1.69),没有回流(p?<0.001; RR 2.28; 95%CI 1.46-3.57),长期全部死亡率(P?<〜0.001; RR 3.82; 95%CI 2.94-4.96),心脏死亡率(p?= 0.004; rr 3.02; 95%ci 1.41-6.45),立柱(p?0.001; rr 2.49; 95%ci 1.47-4.23)和非缺乏mi(p?= 0.46; rr 1.32 ; 95%CI 0.63-2.75)。 Meta分析表明,NLR是PCI后STEMI患者的住院和长期预后的预测因子,但需要通过大型随机临床试验进一步确认。

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