Promoter Sequence for Stringent Control of Bacterial Ribonucleic Acid Synthesis

摘要

In bacterial promoters subject to stringent control the heptanucleotide sequence spanning nucleotide positions ?5 to +2 (defining the ?10 region [D. Pribnow, J. Mol. Biol. >99:419–443, 1975] as positions ?12 to ?6) is highly conserved. This conserved region, for which the best consensus sequence is [Formula: see text] is absent from promoters which are not under stringent control.